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Cryo-EM structure of adeno-associated virus 4 at 2.2 Å resolution

Adeno-associated virus (AAV) is the vector of choice for several approved gene-therapy treatments and is the basis for many ongoing clinical trials. Various strains of AAV exist (referred to as serotypes), each with their own transfection characteristics. Here, a high-resolution cryo-electron micros...

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Detalles Bibliográficos
Autores principales: Zane, Grant, Silveria, Mark, Meyer, Nancy, White, Tommi, Duan, Rui, Zou, Xiaoqin, Chapman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912921/
https://www.ncbi.nlm.nih.gov/pubmed/36762860
http://dx.doi.org/10.1107/S2059798322012190