Cargando…

Cryo-EM structure of adeno-associated virus 4 at 2.2 Å resolution

Adeno-associated virus (AAV) is the vector of choice for several approved gene-therapy treatments and is the basis for many ongoing clinical trials. Various strains of AAV exist (referred to as serotypes), each with their own transfection characteristics. Here, a high-resolution cryo-electron micros...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zane, Grant, Silveria, Mark, Meyer, Nancy, White, Tommi, Duan, Rui, Zou, Xiaoqin, Chapman, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2023
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912921/ https://www.ncbi.nlm.nih.gov/pubmed/36762860 http://dx.doi.org/10.1107/S2059798322012190

Ejemplares similares

Adeno-Associated Virus Receptor-Binding: Flexible Domains and Alternative Conformations through Cryo-Electron Tomography of Adeno-Associated Virus 2 (AAV2) and AAV5 Complexes
por: Hu, Guiqing, et al.
Publicado: (2022)

Adeno-Associated Virus (AAV-DJ)—Cryo-EM Structure at 1.56 Å Resolution
por: Xie, Qing, et al.
Publicado: (2020)

The Structure of an AAV5-AAVR Complex at 2.5 Å Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors
por: Silveria, Mark A., et al.
Publicado: (2020)

Adeno-Associated Virus (AAV) Gene Delivery: Dissecting Molecular Interactions upon Cell Entry
por: Large, Edward E., et al.
Publicado: (2021)

Cross-Species Permissivity: Structure of a Goat Adeno-Associated Virus and Its Complex with the Human Receptor AAVR
por: Large, Edward E., et al.
Publicado: (2022)

Cryo-electron Microscopy of Adeno-associated Virus
por: Stagg, Scott M., et al.
Publicado: (2022)

AlphaFold2 and CryoEM: Revisiting CryoEM modeling in near-atomic resolution density maps
por: Hryc, Corey F., et al.
Publicado: (2022)

Cryo-EM structure of the Slo2.2 Na(+)-activated K(+) channel
por: Hite, Richard, et al.
Publicado: (2015)

The Local Resolution of Cryo-EM Density Maps
por: Kucukelbir, Alp, et al.
Publicado: (2013)

The cryo-EM resolution revolution and transcription complexes
por: Hanske, Jonas, et al.
Publicado: (2018)

Single-particle cryo-EM: beyond the resolution
por: Armache, Jean-Paul, et al.
Publicado: (2019)

Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures
por: Xiao, Hao, et al.
Publicado: (2023)

CryoEM analysis of small plant biocatalysts at sub-2 Å resolution
por: Dimos, Nicole, et al.
Publicado: (2022)

Uniform thin ice on ultraflat graphene for high-resolution cryo-EM
por: Zheng, Liming, et al.
Publicado: (2022)

Cryo-EM reconstruction of the chlororibosome to 3.2 Å resolution within 24 h
por: Forsberg, Björn O., et al.
Publicado: (2017)

Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 Å resolution
por: Pellegrino, Simone, et al.
Publicado: (2023)

High-resolution cryo-EM proteasome structures in drug development
por: Morris, Edward P., et al.
Publicado: (2017)

High-resolution cryo-EM reconstructions in the presence of substantial aberrations
por: Bromberg, Raquel, et al.
Publicado: (2020)

Automatic local resolution-based sharpening of cryo-EM maps
por: Ramírez-Aportela, Erney, et al.
Publicado: (2019)

CryoEM structure of the mature dengue virus at 3.5-Å resolution
por: Zhang, Xiaokang, et al.
Publicado: (2012)

High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase
por: Yang, Lu, et al.
Publicado: (2023)

Estimating loop length from CryoEM images at medium resolutions
por: McKnight, Andrew, et al.
Publicado: (2013)

On the explicit use of experimental images in high resolution cryo-EM reﬁnement
por: Cherfils, Jacqueline, et al.
Publicado: (2019)

Microfluidic protein isolation and sample preparation for high-resolution cryo-EM
por: Schmidli, Claudio, et al.
Publicado: (2019)

Reliable cryo-EM resolution estimation with modified Fourier shell correlation
por: Penczek, Pawel A.
Publicado: (2020)

Dynamics in the murine norovirus capsid revealed by high-resolution cryo-EM
por: Snowden, Joseph S., et al.
Publicado: (2020)

Measuring local-directional resolution and local anisotropy in cryo-EM maps
por: Vilas, Jose Luis, et al.
Publicado: (2020)

Interpretation of medium resolution cryoEM maps of multi-protein complexes
por: Casañal, Ana, et al.
Publicado: (2019)

Principal component analysis is limited to low-resolution analysis in cryoEM
por: Sorzano, Carlos Oscar S., et al.
Publicado: (2021)

Measuring the effects of ice thickness on resolution in single particle cryo-EM
por: Neselu, Kasahun, et al.
Publicado: (2023)

High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217
por: Li, Fenglin, et al.
Publicado: (2023)

Mechanisms of assembly and genome packaging in an RNA virus revealed by high-resolution cryo-EM
por: Hesketh, Emma L., et al.
Publicado: (2015)

Cryo-EM structure of mouse TRPML2 in lipid nanodiscs
por: Song, Xiaojing, et al.
Publicado: (2021)

Cryo-EM structure of the respiratory I + III(2) supercomplex from Arabidopsis thaliana at 2 Å resolution
por: Klusch, Niklas, et al.
Publicado: (2022)

Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM
por: Righetto, Ricardo D., et al.
Publicado: (2019)

Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution
por: Fan, Xiao, et al.
Publicado: (2019)

Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution
por: Cunha, Eva S., et al.
Publicado: (2021)

High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations
por: Jung, James, et al.
Publicado: (2019)

Cryo-EM structure of the autoinhibited state of myosin-2
por: Heissler, Sarah M., et al.
Publicado: (2021)

Cryo-EM structure of a separase-securin complex at near-atomic resolution
por: Boland, Andreas, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7tv175r3djg0radg1v8ui5ro0o