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Netrin-1 Monoclonal Antibody-Functionalized Nanoparticle Loaded with Metformin Prevents the Progression of Abdominal Aortic Aneurysms

BACKGROUND: Abdominal aortic aneurysms (AAAs) are a global health and economic burden. Therapeutic strategies to inhibit the progression of AAAs are currently lacking. Recently, the therapeutic effect of metformin on aneurysms has attracted considerable interest. However, the unfavorable pharmacokin...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiwei, Zhuang, Jiawei, Sun, Daohan, Ding, Qingwei, Zheng, Hui, Li, Haixiang, Zhang, Xiaoyu, Du, Yaming, Ma, Teng, Meng, Qingyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912973/
https://www.ncbi.nlm.nih.gov/pubmed/36777816
http://dx.doi.org/10.2147/IJN.S400993