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Taspase1 Facilitates Topoisomerase IIβ-Mediated DNA Double-Strand Breaks Driving Estrogen-Induced Transcription

The human protease Taspase1 plays a pivotal role in developmental processes and cancerous diseases by processing critical regulators, such as the leukemia proto-oncoprotein MLL. Despite almost two decades of intense research, Taspase1’s biology is, however, still poorly understood, and so far its ce...

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Detalles Bibliográficos
Autores principales: Oelschläger, Lisa, Stahl, Paul, Kaschani, Farnusch, Stauber, Roland H., Knauer, Shirley K., Hensel, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913075/
https://www.ncbi.nlm.nih.gov/pubmed/36766705
http://dx.doi.org/10.3390/cells12030363