Potent Inhibition of Macropinocytosis by Niclosamide in Cancer Cells: A Novel Mechanism for the Anticancer Efficacy for the Antihelminthic

SIMPLE SUMMARY: Niclosamide, a drug used to treat tapeworm infection, has been shown to have potential as an anticancer drug. The mechanism proposed for this action is the drug-induced inhibition of multiple signaling pathways. Here we uncover an additional, but novel and hitherto unknown, mechanism...

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Detalles Bibliográficos
Autores principales: Sennoune, Souad R., Nandagopal, Gunadharini Dharmalingam, Ramachandran, Sabarish, Mathew, Marilyn, Sivaprakasam, Sathish, Jaramillo-Martinez, Valeria, Bhutia, Yangzom D., Ganapathy, Vadivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913174/
https://www.ncbi.nlm.nih.gov/pubmed/36765717
http://dx.doi.org/10.3390/cancers15030759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913174/
https://www.ncbi.nlm.nih.gov/pubmed/36765717
http://dx.doi.org/10.3390/cancers15030759

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