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Potent Inhibition of Macropinocytosis by Niclosamide in Cancer Cells: A Novel Mechanism for the Anticancer Efficacy for the Antihelminthic
SIMPLE SUMMARY: Niclosamide, a drug used to treat tapeworm infection, has been shown to have potential as an anticancer drug. The mechanism proposed for this action is the drug-induced inhibition of multiple signaling pathways. Here we uncover an additional, but novel and hitherto unknown, mechanism...
Autores principales: | Sennoune, Souad R., Nandagopal, Gunadharini Dharmalingam, Ramachandran, Sabarish, Mathew, Marilyn, Sivaprakasam, Sathish, Jaramillo-Martinez, Valeria, Bhutia, Yangzom D., Ganapathy, Vadivel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913174/ https://www.ncbi.nlm.nih.gov/pubmed/36765717 http://dx.doi.org/10.3390/cancers15030759 |
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