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Regulatory Functions and Mechanisms of Circular RNAs in Hepatic Stellate Cell Activation and Liver Fibrosis

Chronic liver injury induces the activation of hepatic stellate cells (HSCs) into myofibroblasts, which produce excessive amounts of extracellular matrix (ECM), resulting in tissue fibrosis. If the injury persists, these fibrous scars could be permanent and disrupt liver architecture and function. C...

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Detalles Bibliográficos
Autores principales: Nokkeaw, Archittapon, Thamjamrassri, Pannathon, Tangkijvanich, Pisit, Ariyachet, Chaiyaboot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913196/
https://www.ncbi.nlm.nih.gov/pubmed/36766720
http://dx.doi.org/10.3390/cells12030378