Current State and Future Challenges for PI3K Inhibitors in Cancer Therapy

SIMPLE SUMMARY: Phosphatidylinositol 3-kinase (PI3K) is a key regulator of many cellular processes and its hyperactivation promotes tumor cell growth and survival. A broad evaluation of the upstream and downstream nodes of its pathway allowed the discovery of several PI3K inhibitors (PI3Ki) with ant...

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Detalles Bibliográficos
Autores principales: Sirico, Marianna, D’Angelo, Alberto, Gianni, Caterina, Casadei, Chiara, Merloni, Filippo, De Giorgi, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913212/
https://www.ncbi.nlm.nih.gov/pubmed/36765661
http://dx.doi.org/10.3390/cancers15030703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913212/
https://www.ncbi.nlm.nih.gov/pubmed/36765661
http://dx.doi.org/10.3390/cancers15030703

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