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Identification and Validation of Potentially Clinically Relevant CpG Regions within the Class 2 Tumor Suppressor Gene SFRP1 in Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer is one of the deadliest cancer entities with five-year survival rates of less than 11%. Besides standardly used surgical therapy, available chemotherapies are increasingly used to prolong overall survival. Promoter hypermethylation of the tumor suppressor gene Secre...

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Detalles Bibliográficos
Autores principales: Hauschulz, Maximilian, Villwock, Sophia, Kosinski, Jennifer, Steib, Florian, Heij, Lara Rosaline, Bednarsch, Jan, Knüchel-Clarke, Ruth, Dahl, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913221/
https://www.ncbi.nlm.nih.gov/pubmed/36765639
http://dx.doi.org/10.3390/cancers15030683