Cargando…

Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain

Senescent cells accumulate in the host during the aging process and are associated with age-related pathogeneses, including cancer. Although persistent senescence seems to contribute to many aspects of cellular pathways and homeostasis, the role of senescence in virus-induced human cancer is not wel...

Descripción completa

Detalles Bibliográficos
Autores principales: Pham, Alexander M., Ortiz, Luz E., Lukacher, Aron E., Kwun, Hyun Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913222/
https://www.ncbi.nlm.nih.gov/pubmed/36766726
http://dx.doi.org/10.3390/cells12030380