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Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain
Senescent cells accumulate in the host during the aging process and are associated with age-related pathogeneses, including cancer. Although persistent senescence seems to contribute to many aspects of cellular pathways and homeostasis, the role of senescence in virus-induced human cancer is not wel...
Autores principales: | Pham, Alexander M., Ortiz, Luz E., Lukacher, Aron E., Kwun, Hyun Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913222/ https://www.ncbi.nlm.nih.gov/pubmed/36766726 http://dx.doi.org/10.3390/cells12030380 |
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