Suppression of Cancer Cell Stemness and Drug Resistance via MYC Destabilization by Deubiquitinase USP45 Inhibition with a Natural Small Molecule

SIMPLE SUMMARY: Cancer stem cells (CSCs) play significant roles in cancer development, drug resistance and cancer recurrence. Thus, it is of great importance to study and target the mechanism by which CSCs are regulated. On the basis of our investigations, we have discovered that USP45 as a new deub...

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Detalles Bibliográficos
Autores principales: Tu, Xiao, Li, Chuncheng, Sun, Wen, Tian, Xi, Li, Qiufu, Wang, Shaoxin, Ding, Xiaoling, Huang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913288/
https://www.ncbi.nlm.nih.gov/pubmed/36765885
http://dx.doi.org/10.3390/cancers15030930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913288/
https://www.ncbi.nlm.nih.gov/pubmed/36765885
http://dx.doi.org/10.3390/cancers15030930

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