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Lower Expression of CFTR Is Associated with Higher Mortality in a Meta-Analysis of Individuals with Colorectal Cancer

SIMPLE SUMMARY: The ion channel gene CFTR is a tumor suppressor in colorectal cancer. It is well-established that individuals with cystic fibrosis, caused by biallelic germline mutations in CFTR, are at increased risk of developing colorectal cancer. A population of colorectal cancer patients with n...

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Detalles Bibliográficos
Autores principales: Scott, Patricia, Wang, Shuo, Onyeaghala, Guillaume, Pankratz, Nathan, Starr, Timothy, Prizment, Anna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913301/
https://www.ncbi.nlm.nih.gov/pubmed/36765944
http://dx.doi.org/10.3390/cancers15030989