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Therapeutic Hypothermia after Cardiac Arrest Attenuates Hindlimb Paralysis and Damage of Spinal Motor Neurons and Astrocytes through Modulating Nrf2/HO-1 Signaling Pathway in Rats

Cardiac arrest (CA) and return of spontaneous circulation (ROSC), a global ischemia and reperfusion event, lead to neuronal damage and/or death in the spinal cord as well as the brain. Hypothermic therapy is reported to protect neurons from damage and improve hindlimb paralysis after resuscitation i...

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Detalles Bibliográficos
Autores principales: Ahn, Ji Hyeon, Lee, Tae-Kyeong, Kim, Dae Won, Shin, Myoung Cheol, Cho, Jun Hwi, Lee, Jae-Chul, Tae, Hyun-Jin, Park, Joon Ha, Hong, Seongkweon, Lee, Choong-Hyun, Won, Moo-Ho, Kim, Yang Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913309/
https://www.ncbi.nlm.nih.gov/pubmed/36766758
http://dx.doi.org/10.3390/cells12030414