Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer’s Disease Pathogenesis

Mutations in presenilin 2 (PS2) have been causally linked to the development of inherited Alzheimer’s disease (AD). Besides its role as part of the γ-secretase complex, mammalian PS2 is also involved, as an individual protein, in a growing number of cell processes, which result altered in AD. To gai...

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Detalles Bibliográficos
Autores principales: Barazzuol, Lucia, Cieri, Domenico, Facchinello, Nicola, Calì, Tito, Washbourne, Philip, Argenton, Francesco, Pizzo, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913325/
https://www.ncbi.nlm.nih.gov/pubmed/36766721
http://dx.doi.org/10.3390/cells12030376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913325/
https://www.ncbi.nlm.nih.gov/pubmed/36766721
http://dx.doi.org/10.3390/cells12030376

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