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F-Box Protein 43, Stabilized by N6-Methyladenosine Methylation, Enhances Hepatocellular Carcinoma Cell Growth and Invasion via Promoting p53 Degradation in a Ubiquitin Conjugating Enzyme E2 C-Dependent Manner

SIMPLE SUMMARY: The role of FBXO43 and the underlying mechanism in cancer are largely unknown. In the present study, we investigated the expression, clinical and prognostic value, and functions of FBXO43 in HCC. The results demonstrated that FBXO43 was upregulated in HCC, was positively associated w...

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Detalles Bibliográficos
Autores principales: Zhou, Huijun, Zeng, Chong, Liu, Jie, Luo, Haijun, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913344/
https://www.ncbi.nlm.nih.gov/pubmed/36765911
http://dx.doi.org/10.3390/cancers15030957