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c-MYC-Driven Polyamine Metabolism in Ovarian Cancer: From Pathogenesis to Early Detection and Therapy

SIMPLE SUMMARY: This review informs on how the MYC signaling is dysregulated and participates in ovarian cancer progression, and the unmet challenge to directly target MYC for ovarian cancer treatment. Therefore, we proposed to alternatively target essential downstream polyamine metabolism pathway o...

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Detalles Bibliográficos
Autores principales: Chen, Yihui, León-Letelier, Ricardo A., Abdel Sater, Ali Hussein, Vykoukal, Jody, Dennison, Jennifer B., Hanash, Samir, Fahrmann, Johannes F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913358/
https://www.ncbi.nlm.nih.gov/pubmed/36765581
http://dx.doi.org/10.3390/cancers15030623