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c-MYC-Driven Polyamine Metabolism in Ovarian Cancer: From Pathogenesis to Early Detection and Therapy
SIMPLE SUMMARY: This review informs on how the MYC signaling is dysregulated and participates in ovarian cancer progression, and the unmet challenge to directly target MYC for ovarian cancer treatment. Therefore, we proposed to alternatively target essential downstream polyamine metabolism pathway o...
Autores principales: | Chen, Yihui, León-Letelier, Ricardo A., Abdel Sater, Ali Hussein, Vykoukal, Jody, Dennison, Jennifer B., Hanash, Samir, Fahrmann, Johannes F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913358/ https://www.ncbi.nlm.nih.gov/pubmed/36765581 http://dx.doi.org/10.3390/cancers15030623 |
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