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Perturbation of Autophagy by a Beclin 1-Targeting Stapled Peptide Induces Mitochondria Stress and Inhibits Proliferation of Pancreatic Cancer Cells
SIMPLE SUMMARY: Autophagy has long been regarded as playing both pro- and anti-proliferative roles in many types of cancer, including PDAC. As the autophagy inhibitor CQ failed to show therapeutic efficacy in PDAC clinical trials, it is worth exploring whether the alternative approach, i.e., elevati...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913477/ https://www.ncbi.nlm.nih.gov/pubmed/36765914 http://dx.doi.org/10.3390/cancers15030953 |