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2,2-Diphenethyl Isothiocyanate Enhances Topoisomerase Inhibitor-Induced Cell Death and Suppresses Multi-Drug Resistance 1 in Breast Cancer Cells
SIMPLE SUMMARY: Mutations in the p53 gene frequently occur in human cancers. The mutations are localized to “hotspot” residues and are classified as structural or contact mutants. p53 mutations disable wild-type (WT) p53 activity; they exert a “dominant negative” effect on WT p53 activity or a “gain...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913484/ https://www.ncbi.nlm.nih.gov/pubmed/36765888 http://dx.doi.org/10.3390/cancers15030928 |