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Amino Acid-Metabolizing Enzymes in Advanced High-Grade Serous Ovarian Cancer Patients: Value of Ascites as Biomarker Source and Role for IL4I1 and IDO1

SIMPLE SUMMARY: Ovarian cancer is the most lethal gynecological malignancy in the United States. Despite the success of immunotherapy for treatment of various cancer types, its impact on ovarian cancer is restrained by a highly immunosuppressive tumor microenvironment. We aimed to evaluate the contr...

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Detalles Bibliográficos
Autores principales: Grobben, Yvonne, den Ouden, Judith E., Aguado, Cristina, van Altena, Anne M., Kraneveld, Aletta D., Zaman, Guido J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913486/
https://www.ncbi.nlm.nih.gov/pubmed/36765849
http://dx.doi.org/10.3390/cancers15030893