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Priming of Colorectal Tumor-Associated Fibroblasts with Zoledronic Acid Conjugated to the Anti-Epidermal Growth Factor Receptor Antibody Cetuximab Elicits Anti-Tumor Vδ2 T Lymphocytes

SIMPLE SUMMARY: Different cells present in the tumor microenvironment can deeply influence both cancer spreading and the success of therapy in solid tumors, including colorectal carcinoma (CRC). In particular, tumor-associated fibroblasts (TAF) exert potent immunosuppressive effects leading to the i...

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Detalles Bibliográficos
Autores principales: Fernandez, Jordi Leonardo Castrillo, Benelli, Roberto, Costa, Delfina, Campioli, Alessio, Tavella, Sara, Zocchi, Maria Raffaella, Poggi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913507/
https://www.ncbi.nlm.nih.gov/pubmed/36765569
http://dx.doi.org/10.3390/cancers15030610