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Genetic and Chemical Controls of Sperm Fate and Spermatocyte Dedifferentiation via PUF-8 and MPK-1 in Caenorhabditis elegans

Using the nematode C. elegans germline as a model system, we previously reported that PUF-8 (a PUF RNA-binding protein) and LIP-1 (a dual-specificity phosphatase) repress sperm fate at 20 °C and the dedifferentiation of spermatocytes into mitotic cells (termed “spermatocyte dedifferentiation”) at 25...

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Detalles Bibliográficos
Autores principales: Park, Youngyong, Gaddy, Matthew, Hyun, Moonjung, Jones, Mariah E., Aslam, Hafiz M., Lee, Myon Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913519/
https://www.ncbi.nlm.nih.gov/pubmed/36766775
http://dx.doi.org/10.3390/cells12030434