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Significant Tumor Regression after Neoadjuvant Chemotherapy in Gastric Cancer, but Poor Survival of the Patient? Role of MHC Class I Alterations

SIMPLE SUMMARY: The major histocompatibility complex (MHC) class I genes, encompassing the human leukocyte antigen (HLA) class I and the beta-2 microglobulin (B2M) genes, play a key role in neoantigens presentation to the immune system. We analyzed allelic imbalance (AI) of the respective chromosoma...

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Detalles Bibliográficos
Autores principales: Hiltner, Theresa, Szörenyi, Noémi, Kohlruss, Meike, Hapfelmeier, Alexander, Herz, Anna-Lina, Slotta-Huspenina, Julia, Jesinghaus, Moritz, Novotny, Alexander, Lange, Sebastian, Ott, Katja, Weichert, Wilko, Keller, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913563/
https://www.ncbi.nlm.nih.gov/pubmed/36765729
http://dx.doi.org/10.3390/cancers15030771