Vemurafenib and Dabrafenib Downregulates RIPK4 Level

SIMPLE SUMMARY: RIPK4 kinase has oncogenic functions in melanoma and shows high similarity to BRAF protein, making this kinase sensitive to the BRAF inhibitors vemurafenib and dabrafenib. BRAFi downregulates RIPK4 in both BRAF-mutated and wild-type cells. Although downregulation and upregulation of...

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Detalles Bibliográficos
Autores principales: Madej, Ewelina, Brożyna, Anna A., Adamczyk, Agnieszka, Wronski, Norbert, Harazin-Lechowska, Agnieszka, Muzyk, Anna, Makuch, Krzysztof, Markiewicz, Michal, Rys, Janusz, Wolnicka-Glubisz, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913565/
https://www.ncbi.nlm.nih.gov/pubmed/36765875
http://dx.doi.org/10.3390/cancers15030918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913565/
https://www.ncbi.nlm.nih.gov/pubmed/36765875
http://dx.doi.org/10.3390/cancers15030918

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