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Multi-Fold Computational Analysis to Discover Novel Putative Inhibitors of Isethionate Sulfite-Lyase (Isla) from Bilophila wadsworthia: Combating Colorectal Cancer and Inflammatory Bowel Diseases

SIMPLE SUMMARY: Hydrogen sulfide (H(2)S) has been produced by certain gut bacteria and associated with the development of inflammatory bowel disease (IBD) and colon cancer. H(2)S is produced by these bacteria regulate the gut inflammation and cell proliferation. The resulted H(2)S produced by an enz...

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Detalles Bibliográficos
Autores principales: Waqas, Muhammad, Halim, Sobia Ahsan, Ullah, Atta, Ali, Assim Alaa Mohammed, Khalid, Asaad, Abdalla, Ashraf N., Khan, Ajmal, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913583/
https://www.ncbi.nlm.nih.gov/pubmed/36765864
http://dx.doi.org/10.3390/cancers15030901