Antithymocyte Globulin Inhibits CD8(+) T Cell Effector Functions via the Paracrine Induction of PDL-1 on Monocytes

Background: Antithymocyte globulins (ATG) are T cell-depleting antibodies used in solid organ transplantation for induction therapy in sensitized patients with a high risk of graft rejection. Previously described effects besides the depletion of T cells have suggested additional modes of action and...

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Detalles Bibliográficos
Autores principales: Copic, Dragan, Direder, Martin, Klas, Katharina, Bormann, Daniel, Laggner, Maria, Ankersmit, Hendrik Jan, Mildner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913606/
https://www.ncbi.nlm.nih.gov/pubmed/36766722
http://dx.doi.org/10.3390/cells12030382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913606/
https://www.ncbi.nlm.nih.gov/pubmed/36766722
http://dx.doi.org/10.3390/cells12030382

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