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Antithymocyte Globulin Inhibits CD8(+) T Cell Effector Functions via the Paracrine Induction of PDL-1 on Monocytes

Background: Antithymocyte globulins (ATG) are T cell-depleting antibodies used in solid organ transplantation for induction therapy in sensitized patients with a high risk of graft rejection. Previously described effects besides the depletion of T cells have suggested additional modes of action and...

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Detalles Bibliográficos
Autores principales:	Copic, Dragan, Direder, Martin, Klas, Katharina, Bormann, Daniel, Laggner, Maria, Ankersmit, Hendrik Jan, Mildner, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913606/ https://www.ncbi.nlm.nih.gov/pubmed/36766722 http://dx.doi.org/10.3390/cells12030382

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