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Intestinal Epithelial Cells Adapt to Chronic Inflammation through Partial Genetic Reprogramming

SIMPLE SUMMARY: Chronic inflammation, as observed in Crohn’s disease and ulcerative colitis patients, damages the intestinal mucosa. We reasoned that if a subset of intestinal epithelial cells adapt to this inflammatory stress to survive, this adaptation could contribute to their malignant transform...

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Detalles Bibliográficos
Autores principales: Collin, Guillaume, Foy, Jean-Philippe, Aznar, Nicolas, Rama, Nicolas, Wierinckx, Anne, Saintigny, Pierre, Puisieux, Alain, Ansieau, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913703/
https://www.ncbi.nlm.nih.gov/pubmed/36765930
http://dx.doi.org/10.3390/cancers15030973