Cargando…

Intestinal Epithelial Cells Adapt to Chronic Inflammation through Partial Genetic Reprogramming

SIMPLE SUMMARY: Chronic inflammation, as observed in Crohn’s disease and ulcerative colitis patients, damages the intestinal mucosa. We reasoned that if a subset of intestinal epithelial cells adapt to this inflammatory stress to survive, this adaptation could contribute to their malignant transform...

Descripción completa

Detalles Bibliográficos
Autores principales:	Collin, Guillaume, Foy, Jean-Philippe, Aznar, Nicolas, Rama, Nicolas, Wierinckx, Anne, Saintigny, Pierre, Puisieux, Alain, Ansieau, Stéphane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913703/ https://www.ncbi.nlm.nih.gov/pubmed/36765930 http://dx.doi.org/10.3390/cancers15030973

Ejemplares similares

Snail Family Members Unequally Trigger EMT and Thereby Differ in Their Ability to Promote the Neoplastic Transformation of Mammary Epithelial Cells
por: Gras, Baptiste, et al.
Publicado: (2014)

Should We Consider Cancers as Embryonic Diseases or as Consequences of Stem-Cell Deregulation?
por: Bastid, Jérémy, et al.
Publicado: (2008)

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
por: Morel, Anne-Pierre, et al.
Publicado: (2008)

The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells()
por: Jacqueroud, Laurent, et al.
Publicado: (2016)

EMT Inducers Catalyze Malignant Transformation of Mammary Epithelial Cells and Drive Tumorigenesis towards Claudin-Low Tumors in Transgenic Mice
por: Morel, Anne-Pierre, et al.
Publicado: (2012)

Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity
por: Uchuya-Castillo, Joel, et al.
Publicado: (2018)

Senescence versus apoptosis in chemotherapy
por: Ansieau, Stéphane, et al.
Publicado: (2015)

Modulation of Oxidative Stress by Twist Oncoproteins
por: Floc'h, Nicolas, et al.
Publicado: (2013)

EMT or EMT-Promoting Transcription Factors, Where to Focus the Light?
por: Ansieau, Stéphane, et al.
Publicado: (2014)

Plasticity of melanoma and EMT-TF reprogramming
por: Tulchinsky, Eugene, et al.
Publicado: (2013)

A twist for survival and cancer progression
por: Puisieux, A, et al.
Publicado: (2006)

A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes
por: Foy, Jean-Philippe, et al.
Publicado: (2017)

Interhelical loops within the bHLH domain are determinant in maintaining TWIST1–DNA complexes
por: Bouard, Charlotte, et al.
Publicado: (2013)

Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach
por: Bouard, Charlotte, et al.
Publicado: (2017)

Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences
por: Bouard, Charlotte, et al.
Publicado: (2016)

The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It Complicated
por: Gouasmi, Roumaïssa, et al.
Publicado: (2022)

TWIST1 a New Determinant of Epithelial to Mesenchymal Transition in EGFR Mutated Lung Adenocarcinoma
por: Pallier, Karine, et al.
Publicado: (2012)

ABCG2, a novel antigen to sort luminal progenitors of BRCA1(-) breast cancer cells
por: Leccia, Felicia, et al.
Publicado: (2014)

Reprogramming Intestinal Epithelial Cell Polarity by Interleukin-22
por: Delbue, Deborah, et al.
Publicado: (2021)

Age reprogramming: cell rejuvenation by partial reprogramming
por: Singh, Prim B., et al.
Publicado: (2022)

IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T cells
por: Wiche Salinas, Tomas Raul, et al.
Publicado: (2021)

Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial Repair
por: Meriwether, David, et al.
Publicado: (2022)

Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction
por: Kim, Jumee, et al.
Publicado: (2023)

Identification of a Gene-Expression-Based Surrogate of Genomic Instability during Oral Carcinogenesis
por: Truchard, Eléonore, et al.
Publicado: (2022)

Epithelial Cell Inflammasomes in Intestinal Immunity and Inflammation
por: Lei-Leston, Andrea C., et al.
Publicado: (2017)

Neutrophil–Epithelial Crosstalk During Intestinal Inflammation
por: Kang, Le, et al.
Publicado: (2022)

An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity
por: Eri, R D, et al.
Publicado: (2011)

Epigenetic Landscapes Explain Partially Reprogrammed Cells and Identify Key Reprogramming Genes
por: Lang, Alex H., et al.
Publicado: (2014)

Immunological and classical subtypes of oral premalignant lesions
por: Foy, Jean-Philippe, et al.
Publicado: (2018)

CDYL2 Epigenetically Regulates MIR124 to Control NF-κB/STAT3-Dependent Breast Cancer Cell Plasticity
por: Siouda, Maha, et al.
Publicado: (2020)

SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation
por: Južnić, Lea, et al.
Publicado: (2021)

Intestinal Epithelial Cells and the Microbiome Undergo Swift Reprogramming at the Inception of Colonic Citrobacter rodentium Infection
por: Hopkins, Eve G. D., et al.
Publicado: (2019)

Bacterial Signaling at the Intestinal Epithelial Interface in Inflammation and Cancer
por: Coleman, Olivia I., et al.
Publicado: (2018)

Arguments to Support a Viral Origin of Oral Squamous Cell Carcinoma in Non-Smoker and Non-Drinker Patients
por: Foy, Jean-Philippe, et al.
Publicado: (2020)

Intestinal epithelial stem cells do not protect their genome by asymmetric chromosome segregation
por: Escobar, Marion, et al.
Publicado: (2011)

Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation
por: Tejón, Gabriela, et al.
Publicado: (2015)

Inflammation triggers ILC3 patrolling of the intestinal barrier
por: Jarade, Angélique, et al.
Publicado: (2022)

Epigenetic reprogramming in the epithelial-to-mesenchymal transition
por: Hoang, Stephen, et al.
Publicado: (2012)

Quantifying local malignant adaptation in tissue‐specific evolutionary trajectories by harnessing cancer’s repeatability at the genetic level
por: Tokutomi, Natsuki, et al.
Publicado: (2019)

Catestatin Regulates Epithelial Cell Dynamics to Improve Intestinal Inflammation
por: Eissa, Nour, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_64clq0se8hcnl1p2e10au14s6q