The Sesquiterpene Lactone-Rich Fraction of Inula helenium L. Enhances the Antitumor Effect of Anti-PD-1 Antibody in Colorectal Cancer: Integrative Phytochemical, Transcriptomic, and Experimental Analyses

SIMPLE SUMMARY: Alantolactone and isoalantolactone—active sesquiterpene lactones of Inula helenium L.—have been reported to suppress tumor growth and modulate immune function; however, the potential for these compounds to regulate cancer immunity is unknown. In this study, a combination of phytochem...

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Detalles Bibliográficos
Autores principales: Chun, Jaemoo, Park, Sang-Min, Lee, Minsung, Ha, In Jin, Jeong, Mi-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913754/
https://www.ncbi.nlm.nih.gov/pubmed/36765611
http://dx.doi.org/10.3390/cancers15030653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913754/
https://www.ncbi.nlm.nih.gov/pubmed/36765611
http://dx.doi.org/10.3390/cancers15030653

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