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The Sesquiterpene Lactone-Rich Fraction of Inula helenium L. Enhances the Antitumor Effect of Anti-PD-1 Antibody in Colorectal Cancer: Integrative Phytochemical, Transcriptomic, and Experimental Analyses
SIMPLE SUMMARY: Alantolactone and isoalantolactone—active sesquiterpene lactones of Inula helenium L.—have been reported to suppress tumor growth and modulate immune function; however, the potential for these compounds to regulate cancer immunity is unknown. In this study, a combination of phytochem...
Autores principales: | Chun, Jaemoo, Park, Sang-Min, Lee, Minsung, Ha, In Jin, Jeong, Mi-Kyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913754/ https://www.ncbi.nlm.nih.gov/pubmed/36765611 http://dx.doi.org/10.3390/cancers15030653 |
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