Synovial Sarcoma Preclinical Modeling: Integrating Transgenic Mouse Models and Patient-Derived Models for Translational Research

SIMPLE SUMMARY: Synovial sarcoma (SyS) is a rare malignant tumor mainly occurring in children, adolescents, and young adults. SyS displays the pathognomonic t(X;18) translocation resulting in the SS18-SSX fusion protein being able to interact with both the BAF enhancer complexes and polycomb repress...

Descripción completa

Detalles Bibliográficos
Autores principales: Landuzzi, Lorena, Ruzzi, Francesca, Lollini, Pier-Luigi, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913760/
https://www.ncbi.nlm.nih.gov/pubmed/36765545
http://dx.doi.org/10.3390/cancers15030588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913760/
https://www.ncbi.nlm.nih.gov/pubmed/36765545
http://dx.doi.org/10.3390/cancers15030588

Ejemplares similares