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Synovial Sarcoma Preclinical Modeling: Integrating Transgenic Mouse Models and Patient-Derived Models for Translational Research
SIMPLE SUMMARY: Synovial sarcoma (SyS) is a rare malignant tumor mainly occurring in children, adolescents, and young adults. SyS displays the pathognomonic t(X;18) translocation resulting in the SS18-SSX fusion protein being able to interact with both the BAF enhancer complexes and polycomb repress...
Autores principales: | Landuzzi, Lorena, Ruzzi, Francesca, Lollini, Pier-Luigi, Scotlandi, Katia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913760/ https://www.ncbi.nlm.nih.gov/pubmed/36765545 http://dx.doi.org/10.3390/cancers15030588 |
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