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IL-15 Prevents the Development of T-ALL from Aberrant Thymocytes with Impaired DNA Repair Functions and Increased NOTCH1 Activation

SIMPLE SUMMARY: Leukemia is a diverse group of hematopoietic malignancies that cause significant morbidity and mortality in children and adults. Although intensive chemotherapy can cure the majority of T-ALL cases, chemo-resistant and relapse cases have poor prognoses. Treatment of such cases requir...

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Detalles Bibliográficos
Autores principales: Nandi, Madhuparna, Ghosh, Amit, Akbari, Sara Ali, Bobbala, Diwakar, Boucher, Marie-Josée, Menendez, Alfredo, Hoang, Trang, Ilangumaran, Subburaj, Ramanathan, Sheela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913776/
https://www.ncbi.nlm.nih.gov/pubmed/36765626
http://dx.doi.org/10.3390/cancers15030671