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Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition

Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan 1 (SPOCK1) has been reported to play an oncogenic role in certain cancer types; however, the role of SPOCK1 in the progression of clear cell renal cell carcinoma (ccRCC) remains elusive. Here, higher SPOCK1 transcript and protein levels we...

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Detalles Bibliográficos
Autores principales: Lin, Yung-Wei, Wen, Yu-Ching, Hsiao, Chi-Hao, Lai, Feng-Ru, Yang, Shun-Fa, Yang, Yi-Chieh, Ho, Kuo-Hao, Hsieh, Feng-Koo, Hsiao, Michael, Lee, Wei-Jiunn, Chien, Ming-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913795/
https://www.ncbi.nlm.nih.gov/pubmed/36766694
http://dx.doi.org/10.3390/cells12030352