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IQGAP1 Is a Phosphotyrosine-Regulated Scaffold for SH2-Containing Proteins

The scaffold protein IQGAP1 associates with over 150 interactors to influence multiple biological processes. The molecular mechanisms that underly spatial and temporal regulation of these interactions, which are crucial for proper cell functions, remain poorly understood. The receptor tyrosine kinas...

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Detalles Bibliográficos
Autores principales: Thines, Louise, Li, Zhigang, Sacks, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913818/
https://www.ncbi.nlm.nih.gov/pubmed/36766826
http://dx.doi.org/10.3390/cells12030483