ATX-LPA-Dependent Nuclear Translocation of Endonuclease G in Respiratory Epithelial Cells: A New Mode Action for DNA Damage Induced by Crystalline Silica Particles

SIMPLE SUMMARY: Crystalline silica particles (CSi) are carcinogenic; however, their genotoxicity is not well characterized. Indirect evidence suggests that retained particles in peripheral bronchioles activate macrophages, causing chronic ROS production. Using human bronchial epithelia in monocultur...

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Detalles Bibliográficos
Autores principales: Zheng, Huiyuan, Stenius, Ulla, Högberg, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913843/
https://www.ncbi.nlm.nih.gov/pubmed/36765823
http://dx.doi.org/10.3390/cancers15030865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913843/
https://www.ncbi.nlm.nih.gov/pubmed/36765823
http://dx.doi.org/10.3390/cancers15030865

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