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ATX-LPA-Dependent Nuclear Translocation of Endonuclease G in Respiratory Epithelial Cells: A New Mode Action for DNA Damage Induced by Crystalline Silica Particles

SIMPLE SUMMARY: Crystalline silica particles (CSi) are carcinogenic; however, their genotoxicity is not well characterized. Indirect evidence suggests that retained particles in peripheral bronchioles activate macrophages, causing chronic ROS production. Using human bronchial epithelia in monocultur...

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Detalles Bibliográficos
Autores principales:	Zheng, Huiyuan, Stenius, Ulla, Högberg, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913843/ https://www.ncbi.nlm.nih.gov/pubmed/36765823 http://dx.doi.org/10.3390/cancers15030865

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