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Kynurenine Pathway in Diabetes Mellitus—Novel Pharmacological Target?
The tryptophan–kynurenine pathway (Trp–KYN) is the major route for tryptophan conversion in the brain and in the periphery. Kynurenines display a wide range of biological actions (which are often contrasting) such as cytotoxic/cytoprotective, oxidant/antioxidant or pro-/anti-inflammatory. The net ef...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913876/ https://www.ncbi.nlm.nih.gov/pubmed/36766803 http://dx.doi.org/10.3390/cells12030460 |