The Breakthroughs and Caveats of Using Human Pluripotent Stem Cells in Modeling Alzheimer’s Disease

Modeling Alzheimer’s disease (AD) using human-induced pluripotent stem cells (iPSCs) is a field now spanning 15 years. Developments in the field have shown a shift in using simple 2D cortical neuron models to more advanced tri-cultures and 3D cerebral organoids that recapitulate more features of the...

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Detalles Bibliográficos
Autores principales: Sahlgren Bendtsen, Katja Maria, Hall, Vanessa Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913971/
https://www.ncbi.nlm.nih.gov/pubmed/36766763
http://dx.doi.org/10.3390/cells12030420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913971/
https://www.ncbi.nlm.nih.gov/pubmed/36766763
http://dx.doi.org/10.3390/cells12030420

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