Maternal Methyl-Enriched Diet Increases DNMT1, HCN1, and TH Gene Expression and Suppresses Absence Seizures and Comorbid Depression in Offspring of WAG/Rij Rats

The reduced expression of the HCN1 ion channel in the somatosensory cortex (SSC) and mesolimbic dopamine deficiency are thought to be associated with the genesis of spike-wave discharges (SWDs) and comorbid depression in the WAG/Rij rat model of absence epilepsy. This study aimed to investigate whet...

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Detalles Bibliográficos
Autores principales: Sarkisova, Karine Yu., Fedosova, Ekaterina A., Shatskova, Alla B., Rudenok, Margarita M., Stanishevskaya, Vera A., Slominsky, Petr A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914012/
https://www.ncbi.nlm.nih.gov/pubmed/36766503
http://dx.doi.org/10.3390/diagnostics13030398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914012/
https://www.ncbi.nlm.nih.gov/pubmed/36766503
http://dx.doi.org/10.3390/diagnostics13030398

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