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NFATc1 Regulation of Dexamethasone-Induced TGFB2 Expression Is Cell Cycle Dependent in Trabecular Meshwork Cells

Although elevated TGFβ2 levels appear to be a causative factor in glaucoma pathogenesis, little is known about how TGFβ2 expression is regulated in the trabecular meshwork (TM). Here, we investigated if activation of the cytokine regulator NFATc1 controlled transcription of TGFβ2 in human TM cells b...

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Detalles Bibliográficos
Autores principales: Filla, Mark S., Faralli, Jennifer A., Dunn, Caleigh R., Khan, Haania, Peters, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914240/
https://www.ncbi.nlm.nih.gov/pubmed/36766846
http://dx.doi.org/10.3390/cells12030504