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Thalidomide Attenuates Mast Cell Activation by Upregulating SHP-1 Signaling and Interfering with the Action of CRBN

Allergy is a chronic inflammatory disease, and its incidence has increased worldwide in recent years. Thalidomide, which was initially used as an anti-emetic drug but was withdrawn due to its teratogenic effects, is now used to treat blood cancers. Although the anti-inflammatory and immunomodulatory...

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Detalles Bibliográficos
Autores principales: Chang, Hyeun-Wook, Sim, Kyeong-Hwa, Lee, Youn-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914299/
https://www.ncbi.nlm.nih.gov/pubmed/36766811
http://dx.doi.org/10.3390/cells12030469