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Chronic Kidney Disease: Combined Effects of Gene Polymorphisms of Tissue Inhibitors of Metalloproteinase 3, Total Urinary Arsenic, and Blood Lead Concentration

The tissue inhibitor of metalloproteinase 3 (TIMP3) is known to be an anti-fibrotic factor. Arsenic, lead, and cadmium exposure and selenium intake may affect TIMP3 expression. The downregulation of TIMP3 expression is related to kidney fibrosis. Genotypes of TIMP3 are related to hypertension and ca...

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Detalles Bibliográficos
Autores principales: Lin, Ying-Chin, Huang, Ya-Li, Shiue, Horng-Sheng, Hsu, Sheng-Lun, Hsueh, Yu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914449/
https://www.ncbi.nlm.nih.gov/pubmed/36767251
http://dx.doi.org/10.3390/ijerph20031886