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Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood–Brain Barrier Model and Entry to Human Brain Organoids

Nanoparticles (NPs) are the focus of research efforts that aim to develop successful drug delivery systems for the brain. Polypeptide nanocarriers are versatile platforms and combine high functionality with good biocompatibility and biodegradability. The key to the efficient brain delivery of NPs is...

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Detalles Bibliográficos
Autores principales: Mészáros, Mária, Phan, Thi Ha My, Vigh, Judit P., Porkoláb, Gergő, Kocsis, Anna, Páli, Emese K., Polgár, Tamás F., Walter, Fruzsina R., Bolognin, Silvia, Schwamborn, Jens C., Jan, Jeng-Shiung, Deli, Mária A., Veszelka, Szilvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914642/
https://www.ncbi.nlm.nih.gov/pubmed/36766845
http://dx.doi.org/10.3390/cells12030503