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Prothymosin α Plays Role as a Brain Guardian through Ecto-F(1) ATPase-P2Y(12) Complex and TLR4/MD2

Prothymosin alpha (ProTα) was discovered to be a necrosis inhibitor from the conditioned medium of a primary culture of rat cortical neurons under starved conditions. This protein carries out a neuronal cell-death-mode switch from necrosis to apoptosis, which is, in turn, suppressed by a variety of...

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Detalles Bibliográficos
Autor principal: Ueda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914670/
https://www.ncbi.nlm.nih.gov/pubmed/36766838
http://dx.doi.org/10.3390/cells12030496