Cargando…

C/EBPβ Coupled with E2F2 Promoted the Proliferation of hESC-Derived Hepatocytes through Direct Binding to the Promoter Regions of Cell-Cycle-Related Genes

Human embryonic stem cells (hESCs) hold the potential to solve the problem of the shortage of functional hepatocytes in clinical applications and drug development. However, a large number of usable hepatocytes derived from hESCs cannot be effectively obtained due to the limited proliferation capacit...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Shoupei, Wang, Jue, Chen, Sen, Han, Zonglin, Wu, Haibin, Chen, Honglin, Duan, Yuyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914899/
https://www.ncbi.nlm.nih.gov/pubmed/36766839
http://dx.doi.org/10.3390/cells12030497