Cargando…
C/EBPβ Coupled with E2F2 Promoted the Proliferation of hESC-Derived Hepatocytes through Direct Binding to the Promoter Regions of Cell-Cycle-Related Genes
Human embryonic stem cells (hESCs) hold the potential to solve the problem of the shortage of functional hepatocytes in clinical applications and drug development. However, a large number of usable hepatocytes derived from hESCs cannot be effectively obtained due to the limited proliferation capacit...
Autores principales: | Liu, Shoupei, Wang, Jue, Chen, Sen, Han, Zonglin, Wu, Haibin, Chen, Honglin, Duan, Yuyou |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914899/ https://www.ncbi.nlm.nih.gov/pubmed/36766839 http://dx.doi.org/10.3390/cells12030497 |
Ejemplares similares
-
Hepatic Polarized Differentiation Promoted the Maturity and Liver Function of Human Embryonic Stem Cell-Derived Hepatocytes via Activating Hippo and AMPK Signaling Pathways
por: Wang, Jue, et al.
Publicado: (2022) -
Hypoxia drives hematopoiesis with the enhancement of T lineage through eliciting arterial specification of hematopoietic endothelial progenitors from hESC
por: Wang, Ning, et al.
Publicado: (2022) -
3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway
por: Wang, Ning, et al.
Publicado: (2021) -
Transplantation of hESC-derived hepatocytes protects mice from liver injury
por: Tolosa, Laia, et al.
Publicado: (2015) -
Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes
por: Cameron, Kate, et al.
Publicado: (2015)