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Six-month safety follow-up of an adjuvanted SARS-CoV-2 trimeric S-protein subunit vaccine (SCB-2019) in adults: A phase 2/3, double-blind, randomized study

BACKGROUND: We evaluated the safety of SCB-2019, a protein subunit vaccine candidate containing a recombinant SARS-CoV-2 spike (S) trimer fusion protein, combined with CpG-1018/alum adjuvants. METHODS: This ongoing phase 2/3, double-blind, placebo-controlled, randomized trial is being conducted in B...

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Detalles Bibliográficos
Autores principales: Hosain, Romana, Aquino, Peter, Baccarini, Carmen, Smolenov, Igor, Li, Ping, Qin, Haijing, Verhoeven, Carole, Hu, Branda, Huang, Yung, Rubio, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915113/
https://www.ncbi.nlm.nih.gov/pubmed/36868877
http://dx.doi.org/10.1016/j.vaccine.2023.02.018